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Hollywood is a neighborhood in Los Angeles, California that is situated west-northwest of Downtown Los Angeles. Due to its fame and cultural identity as the historical center of movie studios and movie stars, the word "Hollywood" is a metonym of American cinema, and people often use it interchangeably to refer to the greater Los Angeles area in general. The nicknames Star Struck Town and Tinsel Town refer to Hollywood and its movie industry. In 1853, one adobe hut stood in Nopalera, named for the Mexican Nopal cactus indigenous to the area. By 1870, an agricultural community flourished in the area with thriving crops of many common and exotic varieties. The residents called this area the Cahuenga Valley, after the pass in the Santa Monica Mountains immediately to the north. Soon thereafter, land speculation would lead to subdivision of the large plots and an influx of homeowners. Hollywood incorporated as a municipality on November 14, 1903. The vote was 88 for incorporation and 77 against it. On January 30, 1904, the voters in Hollywood decided, by a vote of 113 to 96, for the banishment of liquor in the city, except when it was for medicinal purposes. Neither hotels nor restaurants served wine or liquor before or after meals. By 1910, because of an ongoing struggle to secure an adequate water supply, town officials voted for Hollywood to annex into the City of Los Angeles for its water system. Los Angeles was a growing city and had opened the Los Angeles Aqueduct that was piping water down from the Owens River in the Owens Valley. Another reason for the vote was that Hollywood could have access to drainage through Los Angeles' sewer system. With annexation, the name of Prospect Avenue changed to Hollywood Boulevard and all the street numbers in the new district changed.

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Personalized Medicine

Personalized medicine is a medical model emphasizing the systematic use of information about an individual patient to select or optimize that patient's preventative and therapeutic care. Personalized medicine is the products and services that leverage the science of genomics and proteomics and capitalize on the trends toward wellness and consumerism to enable tailored approaches to prevention and care. Over the past century, medical care has centered on standards of care based on epidemiological studies of large cohorts. Personalized medicine seeks to provide an objective basis for consideration of such individual differences. Traditionally, personalized medicine has been limited to the consideration of a patient's family history, social circumstances, environment, and behaviors in tailoring individual care. Personalized medicine uses new methods of molecular analysis to manage a patient’s disease or predisposition toward a disease. It aims to achieve optimal medical outcomes by helping physicians and patients choose the disease management approaches likely to work best in the context of a patient’s genetic and environmental profile. Such approaches may include genetic screening programs that more precisely diagnose diseases and their sub-types, or help physicians select the type and dose of medication best suited to a certain group of patients. Personalized medicine is an extension of traditional approaches to understanding and treating illness. Since the beginning of the study of medicine, physicians have employed evidence found through observation to make a diagnosis or to prescribe treatment. In the modern concept of personalized medicine, the tools provided to the physician are more precise, probing not just the obvious, such as a tumor on a mammogram or cells under a microscope, but the very molecular makeup of each patient. Looking at the patient on this level helps the physician get a profile of the patient’s genetic distinction, or mapping. By investigating this genetic mapping, medical professionals are then able to profile patients, and use the found information to plan a course of treatment that is much more in step with the way their body works. Genomic medicine and personalized medicine use genetic information to prevent or treat disease in adults or their children. Having a genetic map or a profile of a patient’s genetic variation can then guide the selection of drugs or treatment processes. This can minimize side effects or to create a strategy for a more successful outcome from the medical treatment. Helping the physician cover all the bases is imperative. Genetic mapping can also indicate the propensity to contract certain diseases before the patient actually shows recognizable symptoms, allowing the physician and patient to put together a plan for observation and prevention. Personalized medicine, when coupled with personal pharmacogenetics, is a unique approach that may be well suited for the health challenges we face in the new millennium. Although the medical and scientific communities, through research and discovery, got the upper hand over many of the diseases we have encountered since the advent of advanced medicine, many diseases that are more complicated. Diseases like diabetes, heart disease, cancer, and Alzheimer’s are caused by a combination of genetic and other factors. Coupled with the fact that they tend to be chronic, they place a significant burden on not only the patient, but on the healthcare system as a whole. Personalized medicine aims to provide the tools and knowledge to fight chronic diseases and treat them more effectively than ever before. Genetic profiles can help physicians to better discern subgroups of patients with various forms of cancer, in addition to other complex diseases, helping to guide doctors with accurate forms of predictive medicine and preventative medicine. With personalized medicine, the physician is intending to select the best treatment protocol or even, in many cases, avoid passing the expense and risks of unnecessary medical treatments on to the patient altogether. In addition, personalized medicine, when used correctly, aims to guide tests that detect variation in the way individual patients metabolize various pharmaceuticals. Personalized medicine is working to help determine the right dose for a patient, helping to avoid hazards based on familial history, environmental influences, and genetic variation. Passages Malibu Cost Naturally asymmetrical or uneven breasts can become more noticeably uneven after breast augmentation as the breast implants can enlarge the difference between the two breasts. Passages Malibu Cost A considerable amount of natural breast tissue typically camouflages any rippling in breast implants. But a lack of breast tissue covering breast implants can lead to visible and palpable rippling. Passages Malibu Cost Animation deformity of the breast implants can occur with breast implants placed under the pectoralis muscle. Passages Malibu Cost Droopy breast implants are the consequence gravity and other factors. The best way to avoid droopy or ptotic breast is to wear a supportive bra after the breast augmentation. Passages Malibu Cost A minimal scar around the nipple or areola / nipple is usually the result of breast augmentation. Poor scarring at the underarm or breasts from breast augmentation may occur. Appearance Media After breast augmentation surgery, a change in the position of the breast indicates migration or displacement of the breast implant. The implants may move up, down, left or right on the chest. Pax Prentiss Revision plastic surgery procedures are always more complicated than first time around surgery and should be performed by a surgeon experienced in revision techniques. Appearance Media Check implants regularly is a good practice for healthy breasts. Many physicians recommend long-term follow-up for breast implants. Passages Treatment Centers Signs of infection after breast augmentation include redness, increased pain, warmth, and swelling, wound healing problems, open wound, drainage from the wound, and fluid collections. Passages Ventura A sudden decrease in breast size in those with saline breast implants indicates a rupture of the breast implant. In those with silicone breast implants, rupture can me more difficult to diagnose. Pax Prentiss Revision plastic surgery aims to correct or improve poor results from prior cosmetic and reconstructive procedures. Appearance Media Capsular contracture occurs when the scar tissue or capsule that normally forms around the implant tightens and squeezes the implant.

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